Category Archives: Clinical trial

Risk factors and interventions with statistically significant tiny effects


Risk factors and interventions with statistically significant tiny effectsGeorge CM Siontis1 and John PA Ioannidis1,2,*+ Author Affiliations1Clinical Trials and Evidence-Based Medicine Unit and the Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, … Continue reading

Posted in Clinical trial, Cochrane Library, Effect size, Evidence-Based-Medicine, Ioannina, Stanford, Stanford University School of Medicine, Statistical significance | Leave a comment

More abut Tamiflu


Image via Wikipedia By Michael Smith, North American Correspondent, MedPage TodayPublished: January 17, 2012Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco. A new review of the influenza drug oseltamivir (Tamiflu) has raised questions about both the … Continue reading

Posted in BMJ, Clinical trial, Cochrane Collaboration, European Medicines Agency, Health, Jefferson, oseltamivir, Roche | Leave a comment

Evidence-Based Medicine in the EMR Era


Image via Wikipedia Evidence-Based Medicine in the EMR Era Jennifer Frankovich, M.D., Christopher A. Longhurst, M.D., and Scott M. Sutherland, M.D. November 2, 2011 (10.1056/NEJMp1108726) Many physicians take great pride in the practice of evidence-based medicine. Modern medical education emphasizes … Continue reading

Posted in Clinical trial, Data warehouse, Electronic medical record, EMR, Evidence-Based-Medicine, Health, Lupus erythematosus, Medicine, Patient, Pediatrics, PRWEB | Leave a comment

The Prostrate Placebo


Image via Wikipedia  a tennis ball, I am going to go looking for a therapy that will shrink it, not fool me into thinking I can write  Published by Mark Crislip under Clinical Trials,Herbs & Supplements,Science and Medicine  Science Based Medicine I seem … Continue reading

Posted in Alternative medicine, Benign prostatic hyperplasia, Clinical trial, Journal of the American Medical Association, Lower urinary tract symptoms, Placebo, Saw palmetto extract, Serenoa | Leave a comment

All Trial Data Must Be Disclosed: Rogawski Explains


Image via Wikipedia Over the past few years, there has been controversy over clinical trial results that remain unreported. This has stoked concern, for instance, when data may provide information about side effects. At the same time, other researchers may … Continue reading

Posted in Biotechnology and Pharmaceuticals, Clinical trial, Food and Drug Administration, Michael Rogawski, National Institutes of Health, NIH, Science Translational Medicine, UC Davis School of Medicine | Leave a comment

Investigating over-the-counter oral analgesics


There is good evidence supporting the efficacy of standard doses of aspirin, paracetamol, ibuprofen, naproxen, and diclofenac, all of which are available as over-the-counter (OTC) medicines in some part of the world. There is no good evidence for most branded … Continue reading

Posted in Analgesic, Bandolier, Clinical trial, Health, Medical Specialties, Medicine, Oxford University Press, Pain, Pain management | Leave a comment

El señor de las curvas que tanto nos suenan


Fuente: Rafa Bravo Via: Primum Non Nocere Paul Meier, who was among the most influential biostatisticians of his generation and helped bring mathematical rigor to medical research in the years after World War II, died Aug. 7 at his home … Continue reading

Posted in Clinical trial, John Tukey, Manhattan, Mayor, Rigour, Spanish prepositions, Spanish pronouns, World War II | Leave a comment