Journal Watch: Infectious Diseases for November 21, 2007


The Effects of HIV Infection on TB

Summary and Comment | Free

Genotypic clusters of TB including ≥1 HIV-infected person were larger, lasted longer, and had shorter periods between cases than did those involving only HIV-uninfected persons.

By Neil M. Ampel, MD

November 21, 2007

Covering: DeRiemer K et al. Am J Respir Crit Care Med 2007 Nov 1; 176:936

The Quantiferon TB Test in Immunocompromised Patients

Summary and Comment | Subscription Required

The Quantiferon TB-2G was more accurate than the standard tuberculin skin test for diagnosing active TB in immunocompromised patients.

By Thomas Glück, MD

November 21, 2007

Covering: Kobashi Y et al. Eur Respir J 2007 Nov 30:945

Short-Course Nitrofurantoin for Uncomplicated Cystitis in Women

Summary and Comment | Subscription Required

A 5-day course of nitrofurantoin is equivalent to 3 days of TMP-SMX for uncomplicated cystitis in women, providing another alternative to fluoroquinolone use.

By Daniel J. Diekema, MD, MS

November 21, 2007

Covering: Gupta K et al. Arch Intern Med 2007 Nov 12; 167:2207

Fungal Infections in Hematopoietic Stem Cell Transplant Recipients

Summary and Comment | Subscription Required

Invasive fungal infections occurred in 3.7% of transplant recipients; incidence and mortality were significantly higher with allogeneic than with autologous transplants.

By Neil M. Ampel, MD

November 21, 2007

Covering: Pagano L et al. Clin Infect Dis 2007 Nov 1; 45:1161

Polio-Like Outbreaks Caused by Enterovirus Type 71

Summary and Comment | Subscription Required

Incidence of neurologic EV71 disease, which clinically resembles poliomyelitis but is caused by a different enterovirus, seems to be increasing.

By Stephen G. Baum, MD

November 21, 2007

Covering: Pérez-Vélez CM et al. Clin Infect Dis 2007 Oct 15; 45:950

Multiple Sclerosis: An EBV Connection?

Summary and Comment | Subscription Required

Persistence and reactivation of Epstein-Barr virus in the central nervous system may play a role in MS immunopathogenesis.

By Larry M. Baddour, MD

November 21, 2007

Covering: Serafini B et al. J Exp Med 2007 Nov 5;

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