AP al dia: Resumenes comentados

Eficacia y seguridad del rimonabant HTML PPT

¿Cuál ha sido el rendimiento en el tiempo de las vacunas sistemáticas? HTML PPT

Pronóstico de las personas que han sufrido un golpe de calor HTML PPT

Riesgo de cáncer de cérvix invasivo en mujeres intervenidas por lesiones intraepiteliales grado 3 HTML PPT

Journal Watch: salud de la mujer

Hysterectomy Associated with Subsequent Stress Incontinence

General Medicine | Summary and Comment | Subscription Required

This large population-based study makes a convincing case for the connection.

By Bruce Soloway, MD

November 1, 2007

Covering: Altman D et al. Lancet 2007 Oct 27; 370:1494

Magos A. Lancet 2007 Oct 27; 370:1462

Hysterectomy: A Risk Factor for Urinary Incontinence?

Women’s Health | Summary and Comment | Free

Hysterectomy increased the risk for stress–urinary-incontinence surgery, particularly within 5 years.

By Anna Wald, MD, MPH

November 1, 2007

Covering: Altman D et al. Lancet 2007 Oct 27; 370:1494

Magos A. Lancet 2007 Oct 27; 370:1462

HPV vs. Pap Smear for Cervical Abnormalities

General Medicine | Summary and Comment | Subscription Required

If such testing represents the best approach to screening, readily available HPV DNA tests will be needed.

By Robert W. Rebar, MD

October 25, 2007

Covering: Naucler P et al. N Engl J Med 2007 Oct 18; 357:1589

Runowicz CD. N Engl J Med 2007 Oct 18; 357:1650

Is HPV Testing Better Than the Pap Smear?

Women’s Health | Summary and Comment | Free

As a screen for cervical neoplasia, HPV testing showed advantages over the Pap smear.

By Andrew M. Kaunitz, MD

October 17, 2007

Covering: Mayrand M-H et al. N Engl J Med 2007 Oct 18; 357:1579

Combined Pap Smear and HPV Testing Improves Cervical Cancer Detection

Infectious Diseases | Summary and Comment | Subscription Required

Incidence of high-grade cervical lesions was 51% higher with combined testing than with Pap smears alone at initial screening but 42% lower at subsequent screenings.

By Neil M. Ampel, MD

October 17, 2007

Covering: Naucler P et al. N Engl J Med 2007 Oct 18; 357:1589

Runowicz CD. N Engl J Med 2007 Oct 18; 357:1650

AP al dia: resumenes comentados

¿El cribado del VPH es eficaz para la prevención del cáncer de cérvix? HTML PPT

Prevalencia de la enfermedad renal crónica en EEUU HTML PPT

Relación entre el IMC y la causa de muerte HTML PPT

Hallazgos incidentales en las RMN craneales HTML PPT

Higher Risk Remains 25 Years After Treatment of Cervical Neoplasia

Higher Risk Remains 25 Years After Treatment of Cervical Neoplasia

Women treated for grade 3 cervical intraepithelial neoplasia (CIN3) are at increased risk for cervical or vaginal cancers up to 25 years later, reports a study published online in BMJ.

Researchers collected data from Swedish national registries on women who had been diagnosed with and treated for CIN3 between 1958 and 2000. Compared with other Swedish women, those with earlier CIN3 diagnoses had an incidence ratio for invasive cervical cancer of 2.3, and the more recent the diagnosis, the higher the risk (those treated in 1991-2000 had almost twice the risk as those treated in 1958-1970). In addition, the risk increase was accelerated among women aged 50 or older at CIN3 diagnosis.

Risks for vaginal cancer were also elevated, but did not show the worsening historical trend that cervical cancers did.

The authors say patients treated for CIN3 should be offered cytologic screening “at regular intervals, preferably for at least 25 years.”

BMJ article (Free abstract; full text requires subscription)

BMJ editorial (Subscription required)