Tag Archives: ensayos clinicos

Deteniendo ensayos clinicos para beneficio. Demasiado bueno para ser verdad?


Stopping Trials Early for Benefit — Too Good to Be True? Be skeptical of results from trials stopped early for benefit. The practice of stopping randomized clinical trials (RCTs) early for benefit overestimates treatment effects, accrues inadequate data on adverse … Continue reading

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Meta-Disc


Meta-DiSc Descarga English version Meta-DiSc es un programa de libre distribución, para la realización de Meta-análisis de estudios de evaluación de pruebas Diagnósticas y de “Screening”. Pulse el botón izquierdo de su ratón para descargar un documento en formato PDF … Continue reading

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Los ensayos clínicos infantiles requieren un control externo


Los ensayos clínicos infantiles requieren un control externo La seguridad en los ensayos clínicos es un aspecto fundamental siempre, pero se convierte en imprescindible cuando se trata de población infantil. Sin embargo, sólo el 2 por ciento de estos experimentos … Continue reading

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Ensayos clinicos


Control Clin Trials. 1996 Feb;17(1):1-12. Related Articles, Links Assessing the quality of reports of randomized clinical trials: is blinding necessary? Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ. Oxford Regional Pain Relief Unit, University … Continue reading

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Calidad de un estudio: escala de Jadad


Quality of Study: A numerical score between 0-5 is assigned as a rough measure of study design/reporting quality (0 being weakest and 5 being strongest). This number is based on a well-established, validated scale developed by Jadad et al. (Jadad … Continue reading

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Anticoagulantes orales


La tolerancia y la seguridad de los anticoagulantes orales en ancianos es peor en las condiciones de uso habituales que en los ensayos clínicos Hylek EM, Evans-Molina C, Shea C, Henault LE, Regan S. Major Hemorrhage and Tolerability of Warfarin … Continue reading

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Harming through prevention?


Fuente NEJM Editor’s Note: On February 15, 2008, after this article had gone to press, the Office for Human Research Protections (OHRP) issued a statement (www.hhs.gov/ohrp/news/recentnews.html#20080215) expressing its new conclusion that Michigan hospitals may continue to implement the checklist developed … Continue reading

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Los ensayos clinicos no siempre son representativos de la poblacion general


By NICKOLAS BAKALAR Published: December 25, 2007 The randomized clinical trial, widely considered the most reliable biomedical research method, can have significant drawbacks, a new study suggests, because patients included may not be representative of the broader population. Skip to … Continue reading

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Escepticemia: Segun un estudio


Gonzalo Casino gcasino@cardiel.net La medicina vista desde Internet y pasada por el saludable filtro del escepticismo. Según un estudio Sobre el totum revolutum de la investigación y los trabajos a medida Nada parece respaldar tanto la veracidad de un mensaje … Continue reading

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Statistics in Medicine — Reporting of Subgroup Analyses in Clinical Trials


Medical research relies on clinical trials to assess therapeutic benefits. Because of the effort and cost involved in these studies, investigators frequently use analyses of subgroups of study participants to extract as much information as possible. Such analyses, which assess … Continue reading

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Sesgo de publicacion o sesgo de financiamiento? * Sign In to E-Mail or Save This * Print * Reprints * Share o Del.icio.us o Digg o Facebook o Newsvine o Permalink Article Tools Sponsored By By ERIC NAGOURNEY Published: November 13, 2007 Sesgo de publicacion o sesgo de financiamiento?


By ERIC NAGOURNEY Published: November 13, 2007 Inhalers are an effective treatment for asthma and other respiratory diseases, but they can have adverse side effects. The conclusions of studies on these effects apparently depend in part on who pays for … Continue reading

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Sesgo de publicacion o sesgo de financiamiento? * Sign In to E-Mail or Save This * Print * Reprints * Share o Del.icio.us o Digg o Facebook o Newsvine o Permalink Article Tools Sponsored By By ERIC NAGOURNEY Published: November 13, 2007 Sesgo de publicacion o sesgo de financiamiento?


By ERIC NAGOURNEY Published: November 13, 2007 Inhalers are an effective treatment for asthma and other respiratory diseases, but they can have adverse side effects. The conclusions of studies on these effects apparently depend in part on who pays for … Continue reading

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Pediatria Basada en la Evidencia


Adolescentes y drogas. Un reto para los profesionales sanitarios Hidalgo Vicario MI, Redondo Romero A. Evid Pediatr. 2007;3:60. [HTM] [PDF] Papel protector de la lactancia materna en las infecciones de la infancia: análisis crítico de la metodología de estudio Paricio … Continue reading

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