Tag Archives: NEJM

Resultados a largo plazo entre stent carotideo versus endarterectomia


Long-Term Results of Carotid Stenting versus Endarterectomy In the SAPPHIRE trial of patients with carotid-artery disease, carotid-artery stenting was not inferior to endarterectomy at 30 days or at 1 year. In this follow-up study, there was no significant difference between … Continue reading

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Fototerapia para la ictericia neonatal


M. Jeffrey Maisels, M.B., B.Ch., and Antony F. McDonagh, Ph.D. PDF PDA Full Text PowerPoint Slide Set CME Exam Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation <!– … Continue reading

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Un estudio cuestiona la utilidad de los modernos antidepresivos


El análisis de 4 fármacos, entre ellos Prozac, revela que no son mejores que el placebo. El estudio incluyó los datos de varios trabajos no publicados previamente. MARÍA VALERIO Se calcula que una de cada seis personas sufrirá depresión a … Continue reading

Posted in Depresion, Industria Farmaceutica, Medicamentos, Noticias | Tagged , , , , , , , , | 2 Comments

Harming through prevention?


Fuente NEJM Editor’s Note: On February 15, 2008, after this article had gone to press, the Office for Human Research Protections (OHRP) issued a statement (www.hhs.gov/ohrp/news/recentnews.html#20080215) expressing its new conclusion that Michigan hospitals may continue to implement the checklist developed … Continue reading

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El copago en actividades preventivas afecta a las clases más desfavorecidas


El estudio de Trivedi publicado en enero en el New England Journal of Medicine trata el tema del copago como mecanismo para la racionalización del uso de los servicios sanitarios. En concreto analizó como el copago afecta al acceso a … Continue reading

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Riesgos cardiovasculares del Mundial de Fútbol


Wilbert-Lampen U, Leistner D, Greven S, Pohl T, Sper S, Völker C et al. Cardiovascular Events during World Cup Soccer. N Engl J Med 2008; 358: 475-483.  R   TC (s)   PDF (s) Introducción Se han detectado asociaciones entre … Continue reading

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Market-Based Failure — A Second Opinion on U.S. Health Care Costs


U.S. health care expenditures rose 6.7% in 2006, the government recently reported. According to the Centers for Medicare and Medicaid Services, total health care expenditures exceeded $2.1 trillion, or more than $7,000 for every American man, woman, and child.1 Medicare … Continue reading

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Ver deportes estresantes dobla el riesgo de emergencias cardiovasculares


Los fanáticos a los deportes pueden enfrentar más del doble de riesgo de eventos cardiovascular al observar partidos estresantes, de acuerdo a un estudio publicado en New England Journal of Medicine.La incidencia de emergencias cardiovasculares entre residentes alemantes durante partidos … Continue reading

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Endovascular Repair of Abdominal Aortic Aneurysm


Endovascular Repair of Abdominal Aortic Aneurysm The use of an abdominal aortic stent–graft for repair of an abdominal aortic aneurysm is associated with lower early mortality than open surgical repair but also with a higher risk of subsequent need for … Continue reading

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Reparación de aneurismas aórticos endovascular VS abierta


Los pacientes que se someten a reparación de aneurismas aórticos abdominales tienen una mejor supervivencia a corto término cuando son intervenidos con el abordaje endovascular, de acuerdo a un estudio en New England Journal of Medicine.Usando datos de Medicare, los … Continue reading

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Ocultan la falta de efectividad de los antidepresivos


NUEVA YORK.– Los laboratorios fabricantes de antidepresivos, como el Prozac (fluoxetina), jamás publicaron los resultados de cerca de un tercio de los ensayos clínicos que hicieron para obtener la aprobación de esos medicamentos, por lo que engañaron así, deliberadamente, a … Continue reading

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Eficacia a largo plazo de 5 años de tratamiento con estatinas


Ford I, Murray H, Packard CJ, Shepherd J,Macfarlane PW, Cobbe SM for the West of Scotland Coronary Prevention Study Group. Long-Term Follow-up of the West of Scotland Coronary Prevention Study. N Engl J Med 2007; 357: 1477-1486.  R   TC … Continue reading

Posted in factor de riesgo cardiovascular, Medicamentos | Tagged , , , , , , , , | 2 Comments

Medicare Says It Won’t Cover Hospital Errors


New York Times: 19/Ago/2007 By ROBERT PEAR WASHINGTON, Aug. 18 — In a significant policy change, Bush administration officials say that Medicare will no longer pay the extra costs of treating preventable errors, injuries and infections that occur in hospitals, … Continue reading

Posted in Infectologia, Sistemas de Salud | Tagged , , , , , | 3 Comments

Efecto de la obesidad en la infancia y la adolescencia sobre el riesgo de cardiopatía isquémica en la vida adulta


Baker JL, Olsen LW, Sørensen IA. Childhood Body-Mass Index and the Risk of Coronary Heart Disease in Adulthood. N Engl J Med 2007; 357: 2329-2337. R TC PDF Introducción En los países occidentales está aumentando la proporción de niños y … Continue reading

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Medicamentos contra el catarro y la tos


Una de las revistas médicas más prestigiosas e influyentes de EEUU, ‘The New England Journal of Medicine’, ha solicitado que las autoridades retiren de forma inmediata de las farmacias las medicinas contra el catarro y la tos para niños. La … Continue reading

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New England Journal of Medicine


Volume 357 — November 29, 2007 — Number 22   Rosuvastatin in Older Patients with Systolic Heart Failure Patent Foramen Ovale and Cryptogenic Stroke in Older Patients Late-Life Depression Manegement of stable coronary disease Eltrombopag for Thrombocytopenia in Patients with … Continue reading

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New England Journal of Medicine


Perspective   Going Dutch — Managed-Competition Health Insurance in the Netherlands A.C. Enthoven and W.P.M.M. van de Ven Dutch Doctors and Their Patients — Effects of Health Care Reform in the Netherlands J.A. Knottnerus and G.H.M. ten Velden Knock Out, … Continue reading

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Blogs de interes: Desde mi balcon…………….Insulinizacion


“Era sobre el 20 de septiembre cuando el “hombre de verbo rápido” apodado Rafa Bravo nos anunciaba en el foro MEDFAM, que se iban a publicar en el NEJM los resultados del 4-T. Me leí el abstrac y contesté:”…pues vaya … Continue reading

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New England Journal of Medicine. Vol. 357. Núm. 22


Originales McHutchison JG, Dusheiko G, Shiffman ML, Rodriguez-Torres M, Sigal S, Bourliere M et al for the TPL102357 Study Group.  Eltrombopag for Thrombocytopenia in Patients with Cirrhosis Associated with Hepatitis C. Págs. 2227-2236 R TC (s) PDF (s)  Bussel JB, Cheng G, Saleh MN, … Continue reading

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Effects of Torcetrapib in Patients at High Risk for Coronary Events


ABSTRACT Background Inhibition of cholesteryl ester transfer protein (CETP) has been shown to have a substantial effect on plasma lipoprotein levels. We investigated whether torcetrapib, a potent CETP inhibitor, might reduce major cardiovascular events. The trial was terminated prematurely because … Continue reading

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Vacunacion antigripal


La gripe sigue siendo una causa muy importante de enfermedad y muerte. Todos los años la gripe y sus complicaciones son responsables de casi 200000 hospitalizaciones y 44000 muertes. Las vacunas frente a la gripe, son seguras y efectivas. De … Continue reading

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Elecciones en EEUU y resurgimientos de reforma de su sistema de salud


Comprehensive health care reform disappeared from the national agenda after the Clinton administration failed to enact universal coverage in 1993 and 1994. Instead, Congress adopted incremental measures that enjoyed bipartisan support, including the State Children’s Health Insurance Program (SCHIP) and … Continue reading

Posted in Sistemas de Salud | Tagged , , , , , | 5 Comments

Cetuximab en el tratamiento de cancer colo-rectal


Background Cetuximab, an IgG1 chimeric monoclonal antibody against epidermal growth factor receptor (EGFR), has activity against colorectal cancers that express EGFR. Methods From December 2003 to August 2005, 572 patients who had colorectal cancer expressing immunohistochemically detectable EGFR and who … Continue reading

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Teriparatide y alendronato en osteoporosis por corticoides


Background Bisphosphonate therapy is the current standard of care for the prevention and treatment of glucocorticoid-induced osteoporosis. Studies of anabolic therapy in patients who are receiving long-term glucocorticoids and are at high risk for fracture are lacking. Methods In an … Continue reading

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